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A-kinase anchoring protein 8L interacts with mTORC1 and promotes cell growth

mTOR complex 1 (mTORC1) senses nutrients to mediate anabolic processes within the cell. Exactly how mTORC1 promotes cell growth remains unclear. Here, we identified a novel mTORC1-interacting protein called protein kinase A anchoring protein 8L (AKAP8L). Using biochemical assays, we found that the N...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Melick, Chase H., Meng, Delong, Jewell, Jenna L.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7278349/
https://ncbi.nlm.nih.gov/pubmed/32312749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC120.012595
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