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Substrate binding in the multidrug transporter MdfA in detergent solution and in lipid nanodiscs
MdfA from Escherichia coli is a prototypical secondary multi-drug (Mdr) transporter that exchanges drugs for protons. MdfA-mediated drug efflux is driven by the proton gradient and enabled by conformational changes that accompany the recruitment of drugs and their release. In this work, we applied d...
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| Publié dans: | Biophys J |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Biophysical Society
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8204392/ https://ncbi.nlm.nih.gov/pubmed/33771471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2021.03.014 |
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