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Manipulating the drug/proton antiport stoichiometry of the secondary multidrug transporter MdfA
Multidrug transporters are integral membrane proteins that use cellular energy to actively extrude antibiotics and other toxic compounds from cells. The multidrug/proton antiporter MdfA from Escherichia coli exchanges monovalent cationic substrates for protons with a stoichiometry of 1, meaning that...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3411955/ https://ncbi.nlm.nih.gov/pubmed/22802625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203632109 |
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