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Manipulating the drug/proton antiport stoichiometry of the secondary multidrug transporter MdfA

Multidrug transporters are integral membrane proteins that use cellular energy to actively extrude antibiotics and other toxic compounds from cells. The multidrug/proton antiporter MdfA from Escherichia coli exchanges monovalent cationic substrates for protons with a stoichiometry of 1, meaning that...

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Hlavní autoři: Tirosh, Osnat, Sigal, Nadejda, Gelman, Amir, Sahar, Nadav, Fluman, Nir, Siemion, Shira, Bibi, Eitan
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411955/
https://ncbi.nlm.nih.gov/pubmed/22802625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203632109
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