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Manipulating the drug/proton antiport stoichiometry of the secondary multidrug transporter MdfA

Multidrug transporters are integral membrane proteins that use cellular energy to actively extrude antibiotics and other toxic compounds from cells. The multidrug/proton antiporter MdfA from Escherichia coli exchanges monovalent cationic substrates for protons with a stoichiometry of 1, meaning that...

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Autors principals: Tirosh, Osnat, Sigal, Nadejda, Gelman, Amir, Sahar, Nadav, Fluman, Nir, Siemion, Shira, Bibi, Eitan
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411955/
https://ncbi.nlm.nih.gov/pubmed/22802625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203632109
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