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The multidrug transporter MdfA deviates from the canonical model of alternating access of MFS Transporters
The prototypic multidrug (Mdr) transporter MdfA from E. coli efflux chemically-dissimilar substrates in exchange for protons. Similar to other transporters, MdfA purportedly functions by alternating access of a central substrate binding pocket to either side of the membrane. Accordingly, MdfA should...
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| Publicado no: | J Mol Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7541688/ https://ncbi.nlm.nih.gov/pubmed/32860775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.08.017 |
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