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A Promiscuous Conformational Switch in the Secondary Multidrug Transporter MdfA
Multidrug (Mdr) transporters are membrane proteins that actively export structurally dissimilar drugs from the cell, thereby rendering the cell resistant to toxic compounds. Similar to substrate-specific transporters, Mdr transporters also undergo substrate-induced conformational changes. However, t...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2781643/ https://ncbi.nlm.nih.gov/pubmed/19808670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.050658 |
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