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A Promiscuous Conformational Switch in the Secondary Multidrug Transporter MdfA

Multidrug (Mdr) transporters are membrane proteins that actively export structurally dissimilar drugs from the cell, thereby rendering the cell resistant to toxic compounds. Similar to substrate-specific transporters, Mdr transporters also undergo substrate-induced conformational changes. However, t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fluman, Nir, Cohen-Karni, Devora, Weiss, Tali, Bibi, Eitan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781643/
https://ncbi.nlm.nih.gov/pubmed/19808670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.050658
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