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A Promiscuous Conformational Switch in the Secondary Multidrug Transporter MdfA

Multidrug (Mdr) transporters are membrane proteins that actively export structurally dissimilar drugs from the cell, thereby rendering the cell resistant to toxic compounds. Similar to substrate-specific transporters, Mdr transporters also undergo substrate-induced conformational changes. However, t...

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Bibliografische gegevens
Hoofdauteurs: Fluman, Nir, Cohen-Karni, Devora, Weiss, Tali, Bibi, Eitan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781643/
https://ncbi.nlm.nih.gov/pubmed/19808670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.050658
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