Attenuated strain of CVB3 with a mutation in the CAR-interacting region protects against both myocarditis and pancreatitis

Coxsackievirus B3 (CVB3), is commonly implicated in myocarditis, which can lead to dilated cardiomyopathy, in addition to causing acute pancreatitis and meningitis. Yet, no vaccines are currently available to prevent this infection. Here, we describe the derivation of a live attenuated vaccine virus...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Lasrado, Ninaad, Gangaplara, Arunakumar, Massilamany, Chandirasegaran, Arumugam, Rajkumar, Shelbourn, Allison, Rasquinha, Mahima T., Basavalingappa, Rakesh H., Delhon, Gustavo, Xiang, Shi-Hua, Pattnaik, Asit K., Steffen, David, Reddy, Jay
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8203608/
https://ncbi.nlm.nih.gov/pubmed/34127684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90434-w
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