Attenuated strain of CVB3 with a mutation in the CAR-interacting region protects against both myocarditis and pancreatitis

Coxsackievirus B3 (CVB3), is commonly implicated in myocarditis, which can lead to dilated cardiomyopathy, in addition to causing acute pancreatitis and meningitis. Yet, no vaccines are currently available to prevent this infection. Here, we describe the derivation of a live attenuated vaccine virus...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Lasrado, Ninaad, Gangaplara, Arunakumar, Massilamany, Chandirasegaran, Arumugam, Rajkumar, Shelbourn, Allison, Rasquinha, Mahima T., Basavalingappa, Rakesh H., Delhon, Gustavo, Xiang, Shi-Hua, Pattnaik, Asit K., Steffen, David, Reddy, Jay
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8203608/
https://ncbi.nlm.nih.gov/pubmed/34127684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90434-w
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