Mutations in the 5’ NTR and the Non-Structural Protein 3A of the Coxsackievirus B3 Selectively Attenuate Myocarditogenicity

The 5’ non-translated region (NTR) is an important molecular determinant that controls replication and virulence of coxsackievirus B (CVB)3. Previous studies have reported many nucleotide (nt) sequence differences in the Nancy strain of the virus, including changes in the 5’ NTR with varying degrees...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Massilamany, Chandirasegaran, Gangaplara, Arunakumar, Basavalingappa, Rakesh H., Rajasekaran, Rajkumar A., Vu, Hiep, Riethoven, Jean-Jack, Steffen, David, Pattnaik, Asit K., Reddy, Jay
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476614/
https://ncbi.nlm.nih.gov/pubmed/26098885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131052
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