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β1-Adrenergic Receptor Contains Multiple IA(k) and IE(k) Binding Epitopes That Induce T Cell Responses with Varying Degrees of Autoimmune Myocarditis in A/J Mice
Myocarditis/dilated cardiomyopathy (DCM) patients can develop autoantibodies to various cardiac antigens and one major antigen is β1-adrenergic receptor (β(1)AR). Previous reports indicate that animals immunized with a β(1)AR fragment encompassing, 197–222 amino acids for a prolonged period can deve...
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| 出版年: | Front Immunol |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5701947/ https://ncbi.nlm.nih.gov/pubmed/29209317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01567 |
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