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Attenuated strain of CVB3 with a mutation in the CAR-interacting region protects against both myocarditis and pancreatitis

Coxsackievirus B3 (CVB3), is commonly implicated in myocarditis, which can lead to dilated cardiomyopathy, in addition to causing acute pancreatitis and meningitis. Yet, no vaccines are currently available to prevent this infection. Here, we describe the derivation of a live attenuated vaccine virus...

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書誌詳細
出版年:Sci Rep
主要な著者: Lasrado, Ninaad, Gangaplara, Arunakumar, Massilamany, Chandirasegaran, Arumugam, Rajkumar, Shelbourn, Allison, Rasquinha, Mahima T., Basavalingappa, Rakesh H., Delhon, Gustavo, Xiang, Shi-Hua, Pattnaik, Asit K., Steffen, David, Reddy, Jay
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8203608/
https://ncbi.nlm.nih.gov/pubmed/34127684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90434-w
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