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HIF-1α and HIF-2α redundantly promote retinal neovascularization in patients with ischemic retinal disease

Therapies targeting VEGF have proven only modestly effective for the treatment of proliferative sickle cell retinopathy (PSR), the leading cause of blindness in patients with sickle cell disease. Here, we shift our attention upstream from the genes that promote retinal neovascularization (NV) to the...

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Bibliografiset tiedot
Julkaisussa:J Clin Invest
Päätekijät: Zhang, Jing, Qin, Yaowu, Martinez, Mireya, Flores-Bellver, Miguel, Rodrigues, Murilo, Dinabandhu, Aumreetam, Cao, Xuan, Deshpande, Monika, Qin, Yu, Aparicio-Domingo, Silvia, Rui, Yuan, Tzeng, Stephany Y., Salman, Shaima, Yuan, Jin, Scott, Adrienne W., Green, Jordan J., Canto-Soler, M. Valeria, Semenza, Gregg L., Montaner, Silvia, Sodhi, Akrit
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8203455/
https://ncbi.nlm.nih.gov/pubmed/34128478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI139202
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