HIF-1α and HIF-2α redundantly promote retinal neovascularization in patients with ischemic retinal disease

Therapies targeting VEGF have proven only modestly effective for the treatment of proliferative sickle cell retinopathy (PSR), the leading cause of blindness in patients with sickle cell disease. Here, we shift our attention upstream from the genes that promote retinal neovascularization (NV) to the...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Zhang, Jing, Qin, Yaowu, Martinez, Mireya, Flores-Bellver, Miguel, Rodrigues, Murilo, Dinabandhu, Aumreetam, Cao, Xuan, Deshpande, Monika, Qin, Yu, Aparicio-Domingo, Silvia, Rui, Yuan, Tzeng, Stephany Y., Salman, Shaima, Yuan, Jin, Scott, Adrienne W., Green, Jordan J., Canto-Soler, M. Valeria, Semenza, Gregg L., Montaner, Silvia, Sodhi, Akrit
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8203455/
https://ncbi.nlm.nih.gov/pubmed/34128478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI139202
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