Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4

Vision loss from ischemic retinopathies commonly results from the accumulation of fluid in the inner retina [macular edema (ME)]. Although the precise events that lead to the development of ME remain under debate, growing evidence supports a role for an ischemia-induced hyperpermeability state regul...

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Detalhes bibliográficos
Main Authors: Xin, Xiaoban, Rodrigues, Murilo, Umapathi, Mahaa, Kashiwabuchi, Fabiana, Ma, Tao, Babapoor-Farrokhran, Savalan, Wang, Shuang, Hu, Jiadi, Bhutto, Imran, Welsbie, Derek S., Duh, Elia J., Handa, James T., Eberhart, Charles G., Lutty, Gerard, Semenza, Gregg L., Montaner, Silvia, Sodhi, Akrit
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767527/
https://ncbi.nlm.nih.gov/pubmed/23959876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217091110
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