Angiopoietin-like 4 is a potent angiogenic factor and a novel therapeutic target for patients with proliferative diabetic retinopathy

Diabetic eye disease is the most common cause of severe vision loss in the working-age population in the developed world, and proliferative diabetic retinopathy (PDR) is its most vision-threatening sequela. In PDR, retinal ischemia leads to the up-regulation of angiogenic factors that promote neovas...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Babapoor-Farrokhran, Savalan, Jee, Kathleen, Puchner, Brooks, Hassan, Syed Junaid, Xin, Xiaoban, Rodrigues, Murilo, Kashiwabuchi, Fabiana, Ma, Tao, Hu, Ke, Deshpande, Monika, Daoud, Yassine, Solomon, Sharon, Wenick, Adam, Lutty, Gerard A., Semenza, Gregg L., Montaner, Silvia, Sodhi, Akrit
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466723/
https://ncbi.nlm.nih.gov/pubmed/26039997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423765112
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