Angiopoietin-like 4 is a potent angiogenic factor and a novel therapeutic target for patients with proliferative diabetic retinopathy

Diabetic eye disease is the most common cause of severe vision loss in the working-age population in the developed world, and proliferative diabetic retinopathy (PDR) is its most vision-threatening sequela. In PDR, retinal ischemia leads to the up-regulation of angiogenic factors that promote neovas...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Babapoor-Farrokhran, Savalan, Jee, Kathleen, Puchner, Brooks, Hassan, Syed Junaid, Xin, Xiaoban, Rodrigues, Murilo, Kashiwabuchi, Fabiana, Ma, Tao, Hu, Ke, Deshpande, Monika, Daoud, Yassine, Solomon, Sharon, Wenick, Adam, Lutty, Gerard A., Semenza, Gregg L., Montaner, Silvia, Sodhi, Akrit
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2015
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466723/
https://ncbi.nlm.nih.gov/pubmed/26039997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423765112
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