HIF-1α and HIF-2α redundantly promote retinal neovascularization in patients with ischemic retinal disease

Therapies targeting VEGF have proven only modestly effective for the treatment of proliferative sickle cell retinopathy (PSR), the leading cause of blindness in patients with sickle cell disease. Here, we shift our attention upstream from the genes that promote retinal neovascularization (NV) to the...

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Foilsithe in:J Clin Invest
Main Authors: Zhang, Jing, Qin, Yaowu, Martinez, Mireya, Flores-Bellver, Miguel, Rodrigues, Murilo, Dinabandhu, Aumreetam, Cao, Xuan, Deshpande, Monika, Qin, Yu, Aparicio-Domingo, Silvia, Rui, Yuan, Tzeng, Stephany Y., Salman, Shaima, Yuan, Jin, Scott, Adrienne W., Green, Jordan J., Canto-Soler, M. Valeria, Semenza, Gregg L., Montaner, Silvia, Sodhi, Akrit
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2021
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8203455/
https://ncbi.nlm.nih.gov/pubmed/34128478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI139202
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