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IL-23 reshapes kidney resident cell metabolism and promotes local kidney inflammation
Interstitial kidney inflammation is present in various nephritides in which serum interleukin 23 (IL-23) is elevated. Here we showed that murine and human renal tubular epithelial cells (TECs) expressing the IL-23 receptor (IL-23R) responded to IL-23 by inducing intracellular calcium flux, enhancing...
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| Vydáno v: | J Clin Invest |
|---|---|
| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Clinical Investigation
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8203450/ https://ncbi.nlm.nih.gov/pubmed/33956666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI142428 |
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