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Systemic lupus erythematosus favors the generation of IL-17 producing double negative T cells
Mature double negative (DN) T cells are a population of αβ T cells that lack CD4 and CD8 coreceptors and contribute to systemic lupus erythematosus (SLE). The splenic marginal zone macrophages (MZMs) are important for establishing immune tolerance, and loss of their number or function contributes to...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7275084/ https://ncbi.nlm.nih.gov/pubmed/32503973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16636-4 |
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