Systemic lupus erythematosus favors the generation of IL-17 producing double negative T cells

Mature double negative (DN) T cells are a population of αβ T cells that lack CD4 and CD8 coreceptors and contribute to systemic lupus erythematosus (SLE). The splenic marginal zone macrophages (MZMs) are important for establishing immune tolerance, and loss of their number or function contributes to...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Li, Hao, Adamopoulos, Iannis E., Moulton, Vaishali R., Stillman, Isaac E., Herbert, Zach, Moon, James J., Sharabi, Amir, Krishfield, Suzanne, Tsokos, Maria G., Tsokos, George C.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7275084/
https://ncbi.nlm.nih.gov/pubmed/32503973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16636-4
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