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N-glycosylated IgG in patients with kidney transplants increases calcium/calmodulin kinase IV in podocytes and causes injury

Transplant glomerulopathy (TG) is a major cause of late allograft loss. Increased urine podocin/creatinine ratio in TG signifies accelerated podocyte loss. The mechanisms that lead to podocyte injury in TG remain unclear. We report that IgG from kidney transplant recipients with TG, but not from tho...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Transplant
Prif Awduron: Bhargava, Rhea, Maeda, Kayaho, Tsokos, Maria G., Pavlakis, Martha, Stillman, Isaac E., Tsokos, George C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8188503/
https://ncbi.nlm.nih.gov/pubmed/32531122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.16140
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