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The insulin receptor family and protein kinase B (Akt) are activated in the heart by alkaline pH and α(1)-adrenergic receptors
Insulin and insulin-like growth factor stimulate protein synthesis and cardioprotection in the heart, acting through their receptors (INSRs, IGF1Rs) and signalling via protein kinase B (PKB, also known as Akt). Protein synthesis is increased in hearts perfused at alkaline pH(o) to the same extent as...
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| Udgivet i: | Biochem J |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Portland Press Ltd.
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8203208/ https://ncbi.nlm.nih.gov/pubmed/34002209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20210144 |
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