Dual-mechanism quenched fluorogenic probe provides selective and rapid detection of cathepsin L activity

Cathepsin L (CTL) is a cysteine protease demonstrating upregulated activity in many disease states. Overlapping substrate specificity makes selective detection of CTL activity difficult to parse from its close homologue CTV and the ubiquitous CTB. Current probes of CTL activity have limited applicat...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:ChemMedChem
Egile Nagusiak: Schleyer, Kelton A., Fetrow, Ben, Fatland, Peter Zannes, Liu, Jun, Chaaban, Maya, Ma, Biwu, Cui, Lina
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8202353/
https://ncbi.nlm.nih.gov/pubmed/33295147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.202000823
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