Ultrasensitive small molecule fluorogenic probe for human heparanase

Heparanase (HPA) is a critical enzyme involved in the remodeling of the extracellular matrix (ECM), and its elevated expression has been linked with diseases such as various types of cancer and inflammation. The detection of heparanase enzymatic activity holds tremendous value in the study of the ce...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Liu, Jun, Schleyer, Kelton A., Bryan, Tyrel L., Xie, Changjian, Seabra, Gustavo, Xu, Yongmei, Kafle, Arjun, Cui, Chao, Wang, Ying, Yin, Kunlun, Fetrow, Benjamin, Henderson, Paul K. P., Fatland, Peter Z., Liu, Jian, Li, Chenglong, Guo, Hua, Cui, Lina
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2020
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8178809/
https://ncbi.nlm.nih.gov/pubmed/34163592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc04872k
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