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Ultrasensitive small molecule fluorogenic probe for human heparanase

Heparanase (HPA) is a critical enzyme involved in the remodeling of the extracellular matrix (ECM), and its elevated expression has been linked with diseases such as various types of cancer and inflammation. The detection of heparanase enzymatic activity holds tremendous value in the study of the ce...

詳細記述

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書誌詳細
出版年:Chem Sci
主要な著者: Liu, Jun, Schleyer, Kelton A., Bryan, Tyrel L., Xie, Changjian, Seabra, Gustavo, Xu, Yongmei, Kafle, Arjun, Cui, Chao, Wang, Ying, Yin, Kunlun, Fetrow, Benjamin, Henderson, Paul K. P., Fatland, Peter Z., Liu, Jian, Li, Chenglong, Guo, Hua, Cui, Lina
フォーマット: Artigo
言語:Inglês
出版事項: The Royal Society of Chemistry 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8178809/
https://ncbi.nlm.nih.gov/pubmed/34163592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc04872k
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