cGAS restricts colon cancer development by protecting intestinal barrier integrity

The DNA-sensing enzyme cyclic guanosine monophosphate-adenosine monophosphate synthase (cGAS) regulates inflammation and immune defense against pathogens and malignant cells. Although cGAS has been shown to exert antitumor effects in several mouse models harboring transplanted tumor cell lines, its...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Hu, Shuiqing, Fang, Yan, Chen, Xiang, Cheng, Tianlei, Zhao, Miaoqing, Du, Mingjian, Li, Tuo, Li, Minghao, Zeng, Zhiqun, Wei, Yonglong, Gu, Zhimin, Zhang, Conggang, Sun, Lijun, Chen, Zhijian J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2021
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8201956/
https://ncbi.nlm.nih.gov/pubmed/34074794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2105747118
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