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cGAS is essential for cellular senescence

Cellular senescence is a natural barrier to tumorigenesis and it contributes to the antitumor effects of several therapies, including radiation and chemotherapeutic drugs. Senescence also plays an important role in aging, fibrosis, and tissue repair. The DNA damage response is a key event leading to...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Yang, Hui, Wang, Hanze, Ren, Junyao, Chen, Qi, Chen, Zhijian J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468617/
https://ncbi.nlm.nih.gov/pubmed/28533362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705499114
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