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NAD(H)-mediated tetramerization controls the activity of Legionella pneumophila phospholipase PlaB
The virulence factor PlaB promotes lung colonization, tissue destruction, and intracellular replication of Legionella pneumophila, the causative agent of Legionnaires’ disease. It is a highly active phospholipase exposed at the bacterial surface and shows an extraordinary activation mechanism by tet...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8201859/ https://ncbi.nlm.nih.gov/pubmed/34074754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2017046118 |
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