Phospholipase PlaB of Legionella pneumophila Represents a Novel Lipase Family: PROTEIN RESIDUES ESSENTIAL FOR LIPOLYTIC ACTIVITY, SUBSTRATE SPECIFICITY, AND HEMOLYSIS

Legionella pneumophila possesses several phospholipases capable of host cell manipulation and lung damage. Recently, we discovered that the major cell-associated hemolytic phospholipase A (PlaB) shares no homology to described phospholipases and is dispensable for intracellular replication in vitro....

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Autores principales: Bender, Jennifer, Rydzewski, Kerstin, Broich, Markus, Schunder, Eva, Heuner, Klaus, Flieger, Antje
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Enzyme Catalysis and Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785646/
https://ncbi.nlm.nih.gov/pubmed/19640837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.026021
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