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NAD(H)-mediated tetramerization controls the activity of Legionella pneumophila phospholipase PlaB

The virulence factor PlaB promotes lung colonization, tissue destruction, and intracellular replication of Legionella pneumophila, the causative agent of Legionnaires’ disease. It is a highly active phospholipase exposed at the bacterial surface and shows an extraordinary activation mechanism by tet...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Diwo, Maurice, Michel, Wiebke, Aurass, Philipp, Kuhle-Keindorf, Katja, Pippel, Jan, Krausze, Joern, Wamp, Sabrina, Lang, Christina, Blankenfeldt, Wulf, Flieger, Antje
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8201859/
https://ncbi.nlm.nih.gov/pubmed/34074754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2017046118
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