NAD(H)-mediated tetramerization controls the activity of Legionella pneumophila phospholipase PlaB

The virulence factor PlaB promotes lung colonization, tissue destruction, and intracellular replication of Legionella pneumophila, the causative agent of Legionnaires’ disease. It is a highly active phospholipase exposed at the bacterial surface and shows an extraordinary activation mechanism by tet...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Diwo, Maurice, Michel, Wiebke, Aurass, Philipp, Kuhle-Keindorf, Katja, Pippel, Jan, Krausze, Joern, Wamp, Sabrina, Lang, Christina, Blankenfeldt, Wulf, Flieger, Antje
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2021
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8201859/
https://ncbi.nlm.nih.gov/pubmed/34074754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2017046118
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