NAD(H)-mediated tetramerization controls the activity of Legionella pneumophila phospholipase PlaB

The virulence factor PlaB promotes lung colonization, tissue destruction, and intracellular replication of Legionella pneumophila, the causative agent of Legionnaires’ disease. It is a highly active phospholipase exposed at the bacterial surface and shows an extraordinary activation mechanism by tet...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Diwo, Maurice, Michel, Wiebke, Aurass, Philipp, Kuhle-Keindorf, Katja, Pippel, Jan, Krausze, Joern, Wamp, Sabrina, Lang, Christina, Blankenfeldt, Wulf, Flieger, Antje
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2021
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8201859/
https://ncbi.nlm.nih.gov/pubmed/34074754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2017046118
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