PRMT5 Selective Inhibitor Enhances Therapeutic Efficacy of Cisplatin in Lung Cancer Cells

As a therapeutic approach, epigenetic modifiers have the potential to enhance the efficacy of chemotherapeutic agents. Protein arginine methyltransferase 5 (PRMT5), highly expressed in lung adenocarcinoma, was identified to be involved in tumorigenesis. In the current study, we examined the potentia...

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Publicado no:Int J Mol Sci
Main Authors: Bajbouj, Khuloud, Ramakrishnan, Rakhee K., Saber-Ayad, Maha, Omar, Hany A., Saheb Sharif-Askari, Narjes, Shafarin, Jasmin, Elmoselhi, Adel B., Ihmaid, Ahmed, AlHaj Ali, Suhib, Alalool, Abdulla, Abdullah, Reem, Hamid, Qutayba
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8201369/
https://ncbi.nlm.nih.gov/pubmed/34200178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22116131
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