IL-13 Augments Histone Demethylase JMJD2B/KDM4B Expression Levels, Activity, and Nuclear Translocation in Airway Fibroblasts in Asthma

PURPOSE: Asthma is one of the most common obstructive pulmonary diseases worldwide. Epigenetic alterations, including DNA methylation and histone modifications, have been reported to contribute to asthma pathogenesis. Since the inflammation mediator and remodeling trigger, IL-13, is known to play a...

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Détails bibliographiques
Publié dans:J Immunol Res
Auteurs principaux: Bajbouj, Khuloud, Hachim, Mahmood Y., Ramakrishnan, Rakhee K., Fazel, Huwaida, Mustafa, Jumana, Alzaghari, Shahed, Eladl, Mahmoud, Shafarin, Jasmin, Olivenstein, Ronald, Hamid, Qutayba
Format: Artigo
Langue:Inglês
Publié: Hindawi 2021
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920726/
https://ncbi.nlm.nih.gov/pubmed/33688506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6629844
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