Enhanced mitophagy in bronchial fibroblasts from severe asthmatic patients

BACKGROUND: Sub-epithelial fibrosis is a characteristic feature of airway remodeling in asthma which correlates with disease severity. Current asthma medications are ineffective in treating fibrosis. In this study, we aimed to investigate the mitochondrial phenotype in fibroblasts isolated from airw...

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Publicado en:PLoS One
Autores principales: Ramakrishnan, Rakhee K., Bajbouj, Khuloud, Hachim, Mahmood Y., Mogas, Andrea K., Mahboub, Bassam, Olivenstein, Ronald, Hamoudi, Rifat, Halwani, Rabih, Hamid, Qutayba
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2020
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704010/
https://ncbi.nlm.nih.gov/pubmed/33253229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0242695
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