Enhanced mitophagy in bronchial fibroblasts from severe asthmatic patients

BACKGROUND: Sub-epithelial fibrosis is a characteristic feature of airway remodeling in asthma which correlates with disease severity. Current asthma medications are ineffective in treating fibrosis. In this study, we aimed to investigate the mitochondrial phenotype in fibroblasts isolated from airw...

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Bibliographic Details
Published in:PLoS One
Main Authors: Ramakrishnan, Rakhee K., Bajbouj, Khuloud, Hachim, Mahmood Y., Mogas, Andrea K., Mahboub, Bassam, Olivenstein, Ronald, Hamoudi, Rifat, Halwani, Rabih, Hamid, Qutayba
Format: Artigo
Language:Inglês
Published: Public Library of Science 2020
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704010/
https://ncbi.nlm.nih.gov/pubmed/33253229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0242695
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