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Enhanced mitophagy in bronchial fibroblasts from severe asthmatic patients

BACKGROUND: Sub-epithelial fibrosis is a characteristic feature of airway remodeling in asthma which correlates with disease severity. Current asthma medications are ineffective in treating fibrosis. In this study, we aimed to investigate the mitochondrial phenotype in fibroblasts isolated from airw...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Ramakrishnan, Rakhee K., Bajbouj, Khuloud, Hachim, Mahmood Y., Mogas, Andrea K., Mahboub, Bassam, Olivenstein, Ronald, Hamoudi, Rifat, Halwani, Rabih, Hamid, Qutayba
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704010/
https://ncbi.nlm.nih.gov/pubmed/33253229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0242695
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