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Regulation of the JMJD3 (KDM6B) histone demethylase in glioblastoma stem cells by STAT3
The growth factor and cytokine regulated transcription factor STAT3 is required for the self-renewal of several stem cell types including tumor stem cells from glioblastoma. Here we show that STAT3 inhibition leads to the upregulation of the histone H3K27me2/3 demethylase Jmjd3 (KDM6B), which can re...
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| Veröffentlicht in: | PLoS One |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5383422/ https://ncbi.nlm.nih.gov/pubmed/28384648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174775 |
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