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Estrogen-dependent disruption of intracellular iron metabolism augments the cytotoxic effects of doxorubicin in select breast and ovarian cancer cells
Introduction: Increased iron content in cancer cells is associated with resistance to chemotherapy. Recent studies have demonstrated that estrogen (E(2)) suppresses hepcidin synthesis and enhances intracellular iron efflux. Herein, we investigated whether E(2)-driven intracellular iron efflux render...
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| Publicado no: | Cancer Manag Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6536718/ https://ncbi.nlm.nih.gov/pubmed/31213891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S204852 |
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