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Estrogen-dependent disruption of intracellular iron metabolism augments the cytotoxic effects of doxorubicin in select breast and ovarian cancer cells
Introduction: Increased iron content in cancer cells is associated with resistance to chemotherapy. Recent studies have demonstrated that estrogen (E(2)) suppresses hepcidin synthesis and enhances intracellular iron efflux. Herein, we investigated whether E(2)-driven intracellular iron efflux render...
Gorde:
| Argitaratua izan da: | Cancer Manag Res |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Dove
2019
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6536718/ https://ncbi.nlm.nih.gov/pubmed/31213891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S204852 |
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