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Estrogen Signaling Induces Mitochondrial Dysfunction-Associated Autophagy and Senescence in Breast Cancer Cells

Previous work has shown that although estrogen (E2) disrupts cellular iron metabolism and induces oxidative stress in breast and ovarian cancer cells, it fails to induce apoptosis. However, E2 treatment was reported to enhance the apoptotic effects of doxorubicin in cancer cells. This suggests that...

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Detalhes bibliográficos
Publicado no:Biology (Basel)
Main Authors: Bajbouj, Khuloud, Shafarin, Jasmin, Taneera, Jalal, Hamad, Mawieh
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7235898/
https://ncbi.nlm.nih.gov/pubmed/32244623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology9040068
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