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Estrogen Signaling Induces Mitochondrial Dysfunction-Associated Autophagy and Senescence in Breast Cancer Cells

Previous work has shown that although estrogen (E2) disrupts cellular iron metabolism and induces oxidative stress in breast and ovarian cancer cells, it fails to induce apoptosis. However, E2 treatment was reported to enhance the apoptotic effects of doxorubicin in cancer cells. This suggests that...

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Bibliografiske detaljer
Udgivet i:Biology (Basel)
Main Authors: Bajbouj, Khuloud, Shafarin, Jasmin, Taneera, Jalal, Hamad, Mawieh
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7235898/
https://ncbi.nlm.nih.gov/pubmed/32244623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology9040068
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