HGF/c-Met Inhibition as Adjuvant Therapy Improves Outcomes in an Orthotopic Mouse Model of Pancreatic Cancer

SIMPLE SUMMARY: Pancreatic cancer (PC) has a poor prognosis. Even though surgical resection and adjuvant chemotherapy is the most effective therapy, recurrence remains common. In this paper, we investigate the effectiveness of dual inhibition of hepatocyte growth factor (HGF) and c-MET when used as...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Pang, Tony C. Y., Xu, Zhihong, Mekapogu, Alpha Raj, Pothula, Srinivasa, Becker, Therese, Corley, Susan, Wilkins, Marc R., Goldstein, David, Pirola, Romano, Wilson, Jeremy, Apte, Minoti
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8199621/
https://ncbi.nlm.nih.gov/pubmed/34199452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13112763
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