HGF/c-Met Inhibition as Adjuvant Therapy Improves Outcomes in an Orthotopic Mouse Model of Pancreatic Cancer

SIMPLE SUMMARY: Pancreatic cancer (PC) has a poor prognosis. Even though surgical resection and adjuvant chemotherapy is the most effective therapy, recurrence remains common. In this paper, we investigate the effectiveness of dual inhibition of hepatocyte growth factor (HGF) and c-MET when used as...

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Pubblicato in:Cancers (Basel)
Autori principali: Pang, Tony C. Y., Xu, Zhihong, Mekapogu, Alpha Raj, Pothula, Srinivasa, Becker, Therese, Corley, Susan, Wilkins, Marc R., Goldstein, David, Pirola, Romano, Wilson, Jeremy, Apte, Minoti
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8199621/
https://ncbi.nlm.nih.gov/pubmed/34199452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13112763
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