Zinc Finger Protein SALL4 Functions through an AT-Rich Motif to Regulate Gene Expression

The zinc finger transcription factor SALL4 is highly expressed in embryonic stem cells, downregulated in most adult tissues, but reactivated in many aggressive cancers. This unique expression pattern makes SALL4 an attractive therapeutic target. However, whether SALL4 binds DNA directly to regulate...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Cell Rep
Main Authors: Kong, Nikki R., Bassal, Mahmoud A., Tan, Hong Kee, Kurland, Jesse V., Yong, Kol Jia, Young, John J., Yang, Yang, Li, Fudong, Lee, Jonathan D., Liu, Yue, Wu, Chan-Shuo, Stein, Alicia, Luo, Hongbo R., Silberstein, Leslie E., Bulyk, Martha L., Tenen, Daniel G., Chai, Li
Formato: Artigo
Idioma:Inglês
Publicado: 2021
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8197658/
https://ncbi.nlm.nih.gov/pubmed/33406418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108574
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares