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Stem Cell Factor SALL4 Represses the Transcriptions of PTEN and SALL1 through an Epigenetic Repressor Complex
BACKGROUND: The embryonic stem cell (ESC) factor, SALL4, plays an essential role in both development and leukemogenesis. It is a unique gene that is involved in self-renewal in ESC and leukemic stem cell (LSC). METHODOLOGY/PRINCIPAL FINDINGS: To understand the mechanism(s) of SALL4 function(s), we s...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679146/ https://ncbi.nlm.nih.gov/pubmed/19440552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005577 |
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