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Targeting transcription factor SALL4 in acute myeloid leukemia by interrupting its interaction with an epigenetic complex
An exciting recent approach to targeting transcription factors in cancer is to block formation of oncogenic complexes. We investigated whether interfering with the interaction of the transcription factor SALL4, which is critical for leukemic cell survival, and its epigenetic partner complex represen...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3578956/ https://ncbi.nlm.nih.gov/pubmed/23287862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-04-424275 |
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