A SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesis

The embryonic self-renewal factor SALL4 has been implicated in the development of human acute myeloid leukemia (AML). Transgenic mice expressing the human SALL4B allele develop AML, which indicates that this molecule contributes to leukemia development and maintenance. However, the underlying mechan...

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Detalhes bibliográficos
Main Authors: Li, Ailing, Yang, Youyang, Gao, Chong, Lu, Jiayun, Jeong, Ha-Won, Liu, Bee H., Tang, Ping, Yao, Xiaopan, Neuberg, Donna, Huang, Gang, Tenen, Daniel G., Chai, Li
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784519/
https://ncbi.nlm.nih.gov/pubmed/24051379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62891
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