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Exploration of the Zinc Finger Motif in Controlling Activity of Matrix Metalloproteinases

[Image: see text] Discovering ways to control the activity of matrix metalloproteinases (MMPs), zinc-dependent enzymes capable of degrading extracellular matrix proteins, is an important field of cancer research. We report here a novel strategy for assembling MMP inhibitors on the basis of oligopept...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Khrenova, Maria G., Savitsky, Alexander P., Topol, Igor A., Nemukhin, Alexander V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254000/
https://ncbi.nlm.nih.gov/pubmed/25375834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp5088702
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