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Structural Perspectives on the Mechanism of Soluble Guanylate Cyclase Activation

The enzyme soluble guanylate cyclase (sGC) is the prototypical nitric oxide (NO) receptor in humans and other higher eukaryotes and is responsible for transducing the initial NO signal to the secondary messenger cyclic guanosine monophosphate (cGMP). Generation of cGMP in turn leads to diverse physi...

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Pubblicato in:Int J Mol Sci
Autori principali: Wittenborn, Elizabeth C., Marletta, Michael A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8196705/
https://ncbi.nlm.nih.gov/pubmed/34064029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115439
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