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Structural Perspectives on the Mechanism of Soluble Guanylate Cyclase Activation

The enzyme soluble guanylate cyclase (sGC) is the prototypical nitric oxide (NO) receptor in humans and other higher eukaryotes and is responsible for transducing the initial NO signal to the secondary messenger cyclic guanosine monophosphate (cGMP). Generation of cGMP in turn leads to diverse physi...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Wittenborn, Elizabeth C., Marletta, Michael A.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8196705/
https://ncbi.nlm.nih.gov/pubmed/34064029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115439
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