Rutin prevents tau pathology and neuroinflammation in a mouse model of Alzheimer’s disease

BACKGROUND: Tau pathology is a hallmark of Alzheimer’s disease (AD) and other tauopathies. During disease progression, abnormally phosphorylated forms of tau aggregate and accumulate into neurofibrillary tangles, leading to synapse loss, neuroinflammation, and neurodegeneration. Thus, targeting of t...

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Detalles Bibliográficos
Publicado en:J Neuroinflammation
Main Authors: Sun, Xiao-ying, Li, Ling-jie, Dong, Quan-Xiu, Zhu, Jie, Huang, Ya-ru, Hou, Sheng-jie, Yu, Xiao-lin, Liu, Rui-tian
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2021
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8196535/
https://ncbi.nlm.nih.gov/pubmed/34116706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-021-02182-3
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