Rutin prevents tau pathology and neuroinflammation in a mouse model of Alzheimer’s disease

BACKGROUND: Tau pathology is a hallmark of Alzheimer’s disease (AD) and other tauopathies. During disease progression, abnormally phosphorylated forms of tau aggregate and accumulate into neurofibrillary tangles, leading to synapse loss, neuroinflammation, and neurodegeneration. Thus, targeting of t...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Sun, Xiao-ying, Li, Ling-jie, Dong, Quan-Xiu, Zhu, Jie, Huang, Ya-ru, Hou, Sheng-jie, Yu, Xiao-lin, Liu, Rui-tian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8196535/
https://ncbi.nlm.nih.gov/pubmed/34116706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-021-02182-3
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