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Aberrant Bcl-x splicing in cancer: from molecular mechanism to therapeutic modulation
Bcl-x pre-mRNA splicing serves as a typical example to study the impact of alternative splicing in the modulation of cell death. Dysregulation of Bcl-x apoptotic isoforms caused by precarious equilibrium splicing is implicated in genesis and development of multiple human diseases, especially cancers...
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| Publicado no: | J Exp Clin Cancer Res |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8196531/ https://ncbi.nlm.nih.gov/pubmed/34118966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-02001-w |
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