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Cytokine signaling convergence regulates the microglial state transition in Alzheimer’s disease

Genetic analyses have revealed the pivotal contribution of microglial dysfunctions to the pathogenesis of Alzheimer’s disease (AD). Along AD progression, the accumulation of danger-associated molecular patterns (DAMPs) including beta-amyloid and hyperphosphorylated tau continuously stimulates microg...

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Detalhes bibliográficos
Publicado no:Cell Mol Life Sci
Main Authors: Lau, Shun-Fat, Fu, Amy K. Y., Ip, Nancy Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8195901/
https://ncbi.nlm.nih.gov/pubmed/33847763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-021-03810-0
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